Exemestane is an aromatase inhibitor class drug used in bodybuilding to suppress estrogen side effects from steroids. It is also known as Aromasin, which was patented by Upjohn. For the first time antiestrogen appeared on the American market at the beginning of the two thousandth years, immediately after obtaining permission to sell.
Like other members of this class of antiestrogens, Exemestane is widely used in medicine for the treatment of cancer of the breast in women during menopause. However, no less popular was the drug in sports, as it is able to effectively suppress the estrogenic side effects of anabolic steroids. Its mechanism of operation resembles the more popular aromatase inhibitors — Letrozole and Anastrozole. However, in contrast, athletes often use Exemestane in bodybuilding after a steroid cycle.
Positive Effects of Exemestane for Bodybuilding
As mentioned above, Exemestane is able to effectively block the enzyme aromatase, responsible for the process of converting testosterone into female hormones. As a result, the concentration of estrogen in the blood decreases. It is thanks to this drug is effective in the fight against cancer of the breast, as their development is directly related to the growth of estrogen levels. The same fact made Exemestane popular among athletes actively using steroids.
Many anabolic steroids have the ability to aromatize, and this leads to the development of certain side effects, for example, the delay in the body of a large amount of fluid and gynecomastia. The most serious negative effect among them is considered to be the second. However, with active fluid retention can significantly increase blood pressure.
It should also be remembered that not having the ability to aromatize anabolic steroids can also cause the development of estrogenic side effects, if they are inherent in progestogenic activity. A striking example of such steroids are nandrolone esters. This drug weakly interacts with aromatase (not more than 20 percent of testosterone), but it has high progestogenic properties.
Numerous studies have shown that an increase in progesterone levels leads to the development of gynecomastia. Using Exemestane in bodybuilding on a steroid cycle, the athlete will be able to eliminate the risks of estrogen side effects. According to the research, aromazin may reduce the estradiol levels in the blood of 85 percent of the initial figure.
This is not the only positive effect of the drug that made him popular among bodybuilders. The fact is that taking Exemestane in bodybuilding after a steroid cycle can accelerate the processes of secretion of endogenous male hormone. Some athletes do so, including this aromatase inhibitor in the PCT. It should be recognized that Letrozole with Anastrozole also have a similar effect. They can send a signal to the pituitary gland about the need to start the production of hormones of the gonadotropin group — luteinizing and follicle stimulating.
Benefits of Exemestane over Other Aromatase Inhibitor
But Exemestane has some advantages over these drugs:
- It has a low androgenic activity.
- Accelerates the secretion of insulin-like growth factor.
No other representative of the class of aromatase inhibitors has such properties. Using Exemestane in bodybuilding after a steroid cycle, an athlete can not only quickly restore the processes of testosterone synthesis, but by increasing the concentration of insulin-like growth factor shifts the balance between anabolism and catabolism towards the first.
Some bodybuilders believe that this has a positive effect on the recovery of the body, because the effect of rollback is minimized and muscle tissues are protected from destruction. However, if you look at the immediate results of using Exemestane in bodybuilding after a steroid cycle, it becomes clear that it is undesirable to do so. Summing up the results of the conversation about the positive effects of the drug, we highlight the most significant:
- An excellent tool for the prevention of gynecomastia.
- Effectively suppresses the level of female hormones.
- Promotes the growth of anabolic background.
- Improves the relief of muscles.
- It is a good means of preventing hypertension.
- Reduces the negative impact of estrogen on the pituitary arc.