Oxandrolonos 10 or Oxandrolone (Anavar) is a synthetic steroid that has gained fame due to its low androgenic activity. It has the greatest immunostimulating effect, increases insulin sensitivity. The drug was developed initially for the treatment of HIV-infected, burns, diabetes, osteochondrosis, but then began to be used in bodybuilding. Produce the drug under TM Anavar. In therapy, the drug is used to enhance tissue regeneration, contributes to an increase in body weight due to an increase in the weight of muscles and bones.
Since Anavar does not burn weight, a lean muscle mass is formed. Steroid does not retain water, but muscle building is possible. This steroid is not the best way to build muscle, it is inferior to testosterone and other means, but women are more sensitive to it, making the drug effective.
- Oxandrolone, unlike other anabolic steroids, absolutely does not suppress the production of testosterone. Therefore, it does not require the use of any drugs when leaving the “course.”
- In addition, it does not aromatize. That is, during its use, the level of estrogen (female sex hormones) does not increase. It is very convenient. Indeed, in this case, there is no need to use drugs that suppress estrogen. And the risk of gynecomastia in men is absent. And in women, even in large dosages, there is no development of secondary male sexual characteristics. In short, he does not turn women into men and men into women)).
- Oxandrolone is one of the most powerful anti-cartabolic among anabolic steroids. It blocks the receptors for cortisol, which is “guilty” of muscle destruction. Thus, oxandrolone can significantly reduce the rate of muscle breakdown.
- Oxandrolone stimulates the production of creatine phosphate in the muscles. And this directly affects the growth of muscle strength. However, it is useless for gaining muscle mass. That is, the strength from it will grow, but the mass does not. Studies have shown that only significant dosages (100 mg or more per day) can lead to a small weight gain.
Oxandrolone is impractical to use for gaining muscle mass. Oxandrolone cycle is recommended for people who have enough muscle mass and moderate body fat in order to give muscle relief and reduce subcutaneous fat.
Side Effects of Oxandrolone
Although oxandrolone is an alpha-17-alkylated steroid, its toxic effect on the liver is negligible. Studies show that Anavar at a dose of 20 mg per day taken for 12 weeks does not affect the level of liver enzymes (indicators of liver destruction). The first signs of damage to the liver are pain in the right hypochondrium, light stools and dark urine.
Since Anavar is a derivative of dihydrotestosterone, it does not aromatize (does not turn into estrogens, which cause side effects such as gynecomastia and fluid accumulation in the body).
Oxandrolone does not have a significant effect on the level of production of own testosterone in moderate doses (the axis of the hypothalamus-pituitary-testes does not inhibit the feedback mechanism). When the dosage of Anavar is high, the body reacts with a decrease in gonadotropin production, assuming that the endogenous testosterone level is too high. Lack of stimulation of Leydig cells leads to testicular atrophy. Oxandrolone used at a dose of 80 mg per day suppresses testosterone levels after 12 weeks of administration by 67%.
Suppression of testosterone production is manifested by a decrease in libido and sluggish erection. To eliminate this side effect of oxandrolone, you can add to the course of gonadotropin or conduct combined courses with androgenic drugs.
More or less effective dosages of this drug: 50 – 100 mg per day for men, and 20 – 50 mg per day for women and children. And ideally, you need to divide this portion into 3 receptions. This is due to the fact that the half-life of oxandrolone is 8 – 10 hours. And if you divide his reception into three times and take at regular intervals of time, then just get 8 hours.
The fact is that such a device will keep the level of this drug in the body at the same level. And this will slightly increase its effectiveness than if you took it once every 24 hours. In this case, you can not avoid hormonal fluctuations, because after a day in your body, almost nothing will remain from the previous intake. Not that this is bad, but if you can squeeze the maximum out of this drug, then it is better to do so. By the way, the frequency of taking any steroid should be based precisely on the duration of its half-life.
As a rule, dosages of more than 100 mg per day are not advisable. Since the efficiency is almost not growing. And such dosages will be great to beat on your wallet.